Although there are several studies of ASICs in the pathophysiology of glioma cells (Berdiev et al., 2003; Bubien et al., 2004; Kapoor et al., 2009, 2011; Rooj et al., 2012), this study uniquely dives deeper into the connection between weak acidosis activated ASIC1 and its effect on the migration of glioma cells (Sheng et al., 2021). The gene discussed is ASIC1; the disease is central nervous system cancer.