For example, TRPV1 expression is increased in bronchial biopsies from patients with chronic cough (Groneberg et al., 2004; Mitchell et al., 2005), while de novo TRPV1 expression occurs in low-threshold mechanoreceptors after allergen exposure and virus infection in guinea pigs (Lieu et al., 2012; Zaccone et al., 2016) and after allergen exposure in rats (Zhang et al., 2008b, a). The gene discussed is TRPV1; the disease is viral infectious disease.