These factors could be a sudden increase in IL-19 levels within the CNS, increase levels of pro-inflammatory or anti-inflammatory cytokines, or other mechanisms as reported for NSCLC, HUVEC, HMEC, and aortic rings (Hsieh et al., 2006; Hammer et al., 2009; Baird et al., 2011; Kako et al., 2016). Here, IL19 is linked to non-small cell lung carcinoma.