We found that many mutations in genes, such as RP1L1, TP53, CACNA1H, VWF, PKD1L1, and TP53, were highly overrepresented in NB cell lines, each mutation was present in more than 40% cell lines compared to NB patients, in which these mutations were found for less than 1% tumors (Fig. S6a, Table S8). The gene discussed is VWF; the disease is neuroblastoma.