ANGPT2 and acute respiratory distress syndrome: In contrast, Day 7 Ang2 levels decreased in survivors but remained elevated in non-survivors with the optimized cutoff point for ARDS mortality prediction shown in Fig. 4C. Using a cutoff point of 12.1 ng/ml, the sensitivity and specificity of Ang2 as a test for ARDS mortality were 0.45 and 0.89, respectively.