Concurrently, we identified another group of patients (n = 52) who received anti-PD-1/PD-L1 monotherapy and whose pre-treatment cancers were 9p21-WT with largely matched cancer type, gender and therapy as the control cohort, resulting in a solid tumor cohort consisting of 94 patients (Fig. 3a and Supplementary Data 11) for subsequent analysis. Here, CD274 is linked to cancer.