To characterize the pathways that are targeted by APA in lung cancer, we performed a pathway enrichment analysis using IPA32 and found those mRNA transcripts with shorter 3′UTRs were enriched with cell cycle/proliferation pathways often dysregulated in cancer, including mTOR and its target ubiquitin proteolysis pathway, receptor tyrosine kinase signaling and signaling specific to lung cancer. The gene discussed is MTOR; the disease is lung carcinoma.