Thus, the initial serological results of our case (positive IgG and IgM) indicate any of the following profiles: (1) recent primary infection; (2) latent/distant infection of primary infection (with persistent IgM); (3) recent infection of a different strain (reinfection); or (4) recurrence/reactivation of latent infection. The gene discussed is CD40LG; the disease is disease arising from reactivation of latent virus.