The results showed that the expression level of GINS4 was positively correlated with the infiltration levels of B cells (partial cor = 0.44), CD8+ T cells (partial cor = 0.271), CD4+ T cells (partial cor = 0.338), Macrophages (partial cor = 0.436), Neutrophils (partial cor = 0.338) and Dendritic cells (partial cor = 0.412) in low-grade glioma (LGG) tissues (p < 0.05). The gene discussed is GINS4; the disease is central nervous system cancer.