First, we used GEPIA2 (http://gepia2.cancer-pku.cn/) to analyzed the GINS4 expression in tumor tissues, and our results showed that the expression level of GINS4 was increased in a variety of tumors, including glioblastoma (GBM) compared with those in their corresponding NT tissues (Fig. 1A). The gene discussed is GINS4; the disease is glioblastoma.