TOMM20 and systemic lupus erythematosus: In confirmation of our experimental setup, IC-induced NETs stained positive for 8-Oxo-2′-deoxyguanosine (8-OH-dG; a marker of oxidized DNA), TOMM20 (an outer-membrane mitochondrial protein), and citrullinated histone 3 (a marker indicative of the NOX-independent pathway of NETosis), which are all hallmarks of SLE NETosis (16) (Supplemental Figure 3, A and B).