RB1 and retinoblastoma: We hypothesizedthat the association of RB with the lipophilic TF increased the RBcell uptake and consequently the cytostatic effect.6 On the other hand, b-TF did not induce any effect supportingthe thesis of a safe nanocarrier enhancing RB antimelanoma activity.In addition, at 50 μM, a promising selectivity of RB-TF on cancercells compared to fibroblast was noticed.