STING1 and melanoma: In a melanoma mice model, it was reported that an intratumorally-delivered interferon gene (STING) agonist ADU S-100 (5 μg/mouse) increased the production of antiangiogenic factors including TNFSF15 and CXCL10, and TLS-inducing factors including CCL19, CCL21, LTa, LTb, and LIGHT.