STAB1 and hepatocellular carcinoma: Interestingly, early results in patients where biopsies were undertaken did show a reduction of anti-inflammatory intratumoral stabilin-1+macrophages and an increase in proinflammatory/adaptive immune cell subsets in selected patients.176This trial is ongoing and overall therapeutic efficacy is awaited, yet the data are consistent with the detrimental effects of TAM scavenger receptors and their role in driving an immunosuppressive TME, and also highlight therapeutic potential for their targeting within the context of HCC.