DMD and neuromuscular disease caused by qualitative or quantitative defects of dystrophin: A variety of recent reviews provide excellent details on the discovery of dystrophin [130], the genetic basis of dystrophinopathy [84, 117, 228], the complexity of pathophysiological mechanisms that underlie the muscle-related pathogenesis [6, 141, 300, 319, 340], diagnosis and clinical management of Duchenne patients [25–27, 215] and novel therapeutic strategies to treat progressive muscle degeneration and associated complications in X-linked muscular dystrophy [101, 298, 299].