In addition, basic levels of IL‐6 and TNF‐α in mDCs, and basic levels of IFN‐γ and TNF‐α in pDCs were increased in the elderly,44 while chronic low‐grade inflammation (slight increase of inflammatory factors, such as IL‐6 and TNF‐α), atherosclerotic cardiovascular and cerebrovascular diseases, Parkinson's disease, Alzheimer's disease, and other neurodegenerative diseases are closely related to the occurrence of malignant tumors.64 The gene discussed is TNF; the disease is cerebrovascular disorder.