CXCL12 and lung cancer: In addition, the mRNA expression levels of chemokines (CCL2, CCL7, CCL8, CCL13, CXCL4, CXCL9, CXCL10, CXCL11, CXCL12, and CXCL13) corresponding to the four chemokine receptors in various cancers were analyzed using the online Oncomine database (threshold for fold change [FC] > 2, p < 0.05, and rank = top 10), and the results showed that only CXCL13 (unique ligand for CXCR5) expression was elevated in lung cancer (Figure S1).