FoxP3 is the control gene for Tregs, and a study reported the distribution of TILs and FoxP3+ cells in cervical cancer (n = 10) and CIN (n = 8) tissues, showing that CD4+CD25+FoxP3+ Tregs accumulated around the tumor cells and that cervical cancer contained a significantly higher proportion of the FoxP3+ T cells than found in CIN (p < 0.001).78 Here, CD4 is linked to cervical squamous intraepithelial neoplasia.