IL2 and neoplasm: ,93 The production process was divided into several typical steps: the tissue adjacent to the tumor was collected during surgery or biopsy with a diameter of about 0.5–1 cm; after rinsing with 0.9% physiological saline, the tumor sample was transported to a proprietary GMP facility; tumor tissues were mechanically diced and placed in cell cultural plates; and TILs were separated and propagated with a high concentration of IL-2 for selective cultivation.