CD4 and metastatic malignant neoplasm in the lymph nodes: Similarly, the proportion of CD4+ T cells was found to be significantly lower in tumors from patients (stage IA to IIA cervical carcinoma) with lymph node metastasis (n = 8) than in those from patients without lymph node metastasis (n = 22) (24.5 versus 32.7, p = 0.001).