TNF and metabolic dysfunction-associated steatohepatitis: Furthermore, the KEGG enrichment analysis suggested that the pathways of “osteoclast differentiation,” “IL−17 signaling,” “TNF signaling,” “Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling,” “microRNAs in cancer,” “prolactin signaling,” “growth hormone synthesis,” “secretion and action,” “type II diabetes mellitus,” “leishmaniasis,” and “colorectal cancer” might be biological pathways altered in NASH compared with normal tissues (Figure 2(b)).