Sham et al. (68) reported that mean QTc was longer in SLE subjects with, rather than without circulating anti-Ro/SSA-antibodies, while Mostafavi et al. (71) and Perez-Garcia et al. (69) found that anti-Ro/SSA-antibodies were more commonly detectable and at a higher concentration when SLE patients with QTc prolongation were compared to those with a normal QTc. The gene discussed is CALR; the disease is systemic lupus erythematosus.