Clinical studies also showed reduction in laboratory markers for allergy including TNF-α and IL-6 as well as IgE and eosinophil count in nasal discharge and allergic symptoms including nasal mucosal congestion, nasal itching, runny nose, sneezing attacks, turbinate hypertrophy, and mucosal pallor in allergic rhinitis induced by onion, Qt, and kaempferol. Here, IGHE is linked to allergic disease.