Differentially expressed genes in the viral infection category (174 genes, Figure 1D) indicated that keratinocytes had down-regulated genes involved in host gene transcription (DDX56, SMARCA2) (37, 38) and RNA transportation and processing (NUP98, RAE1, XAB2, RBM17, EXOSC10) (39–41). This evidence concerns the gene EXOSC10 and viral infectious disease.