CD8A and neoplasm: Whilst significant expansion of tumor-specific T cells remained following vaccination with IFNβ in I/AEo/o mice, a greater than 3-fold decrease (5.5% vs 1.8%, p < 0.0005) was observed when compared to the percentage of IFNγ+ CD8+ T cells in wildtype C57BL/6 mice (Figure 1D).