Regarding CYP2A subfamily, Chinese people with the deletion of the CYP2A6 gene are more likely to have elevated transaminase after valproate treatment (Zhao et al., 2017; Yoon et al., 2020), which significantly increases the susceptibility of liver injury in patients with epilepsy caused by valproic acid (Tanner and Tyndale, 2017). The gene discussed is CYP2A6; the disease is epilepsy.