In addition, nuclear factor E2-related factor 2 (Nrf2) rs4243387 and MAFF rs2267373 (Chen et al., 2019), inducible nitric oxide synthase (NOS2A), BTB and CNC homology 1 (BACH1) and MAFK (Nanashima et al., 2012) have been shown to be significantly associated with anti-tuberculosis drug-induced hepatotoxicity in Chinese and Japanese populations. Here, NOS2 is linked to tuberculosis.