CYP2B6 and injury: Regarding CYP2B subfamily, the fast metabolic CYP2B6 rs7254579 can increase the susceptibility to ticlopidine-induced liver injury (Ariyoshi et al., 2010), while the slow metabolic CYP2B6 (*6/*6) can increase the susceptibility to Efavirenz-induced liver injury by reducing the activity of metabolic enzymes (Yimer et al., 2012).