In addition, DILI and AIH have similar clinical symptoms in some cases (Chinese Society of Hepatology, Chinese Medical Association, Chinese Society of Gastroenterology, Chinese Medical Association, Chinese Society of Infectious Diseases, Chinese Medical Association, 2016), and it is now possible to enhance the differentiation by sequencing specific HLA alleles (DRB1*03:01 and DRB1*04:01) (de Boer et al., 2017; Zhan et al., 2019). This evidence concerns the gene HLA-DRB1 and autoimmune hepatitis.