The Cell Cycle pathway was correlated with CDK2 and CDK6 overexpression in HCC (R = 0.51, FDR = 2e − 5 and R = 0.39, FDR = 0.01, respectively), also with CDK6 in PRAD (R = 0.4, FDR = 0.025). This evidence concerns the gene CDK2 and hepatocellular carcinoma.