Insulin-like growth factor 1 receptor (IGF1R) was found to show expression-driven dependency by cancer cells of the ovary (R = −0.6, FDR = 6.7E − 3) and lung (R = −0.35, FDR = 0.04); in both cancer cohorts, we also found high IGF1R overexpression rates and hyperphosphorylation of IGF1R p.T1366 (Fig. 5a). The gene discussed is IGF1R; the disease is cancer.