FOXO1 and neoplasm: GSEA revealed that several pathways related to chemotaxis, INF-γ production, and regulation of T cell immunity were inactivated in both Rh-30 siPF and Rh-30 siB7-H3 unlike in Rh30 siCont, suggesting that PAX3-FOXO1 and B7-H3 may contribute to tumor cell metastasis and immune evasion (Fig. 3a,b).