OLFM4 and congenital secretory chloride diarrhea 1: Since the high degree of mortality observed in ACLF is believed to be driven by highly inflammatory innate immune responses, gene expression levels obtained from qRT-PCR experiments for the genes ELANE, MPO, CD177, OLFM4, OLAH (upregulated in ACLF versus CLD or ACLF versus HC) were stratified based on 28-day mortality in ACLF (Fig. 3A-E).