Formalin fixed paraffin embedded (FFPE) liver biopsies from deceased ACLF and CLD-AD (CLD with acute decompensation but without ACLF) were retrospectively retrieved and subjected to dual colour IHC for CD16 and CD177 in order to investigate the tissue localization of the CD177+ neutrophil sub-population (Fig. 5A-D). The gene discussed is CD177; the disease is Alzheimer disease.