We also employed Neo-2/15, an IL-2-mimic that binds to heterodimeric IL-2Rβγ and is unrelated in amino acid sequence and topology to IL-236, which showed the same growth-promoting effect as rhIL-2 in ALCL cells with, but not without, BATF3 expression (Supplementary Fig. 4c, d). The gene discussed is BATF3; the disease is anaplastic large cell lymphoma.