Remarkably, both the AP-1-family member BATF3 and IL-2R components were consistently found among the top SE-associated genes in ALCL cell lines and primary ALCL samples, which attracted our attention for detailed analyses given our previous findings on AP-1/BATF function in ALCL and the important role of IL-2/IL-2R for T lymphocyte growth and function12,18. The gene discussed is IL2RA; the disease is anaplastic large cell lymphoma.