We observed that ZGRF1 expression positively correlates with the mRNA levels of BRCA1 and EXO1 in several types of cancer, including lung adenocarcinoma (LUAD), ovarian (OV), prostate adenocarcinoma (PRAD) and tetrahydrocannabinolic acid (THCA) cancers (Fig. 7A–H), suggesting the regulatory of ZGRF1 and BRCA1/EXO1 exists ubiquitous. This evidence concerns the gene BRCA1 and lung adenocarcinoma.