In line with this, we found that the epithelial markers E-cadherin and α-catenin were increased, whereas the mesenchymal markers N-cadherin, fibronectin, and vimentin were decreased in HCC cell lines upon LNCAROD knockdown (Fig. 2D); LNCAROD overexpression produced the opposite results (Figure S2D), indicating that EMT in HCC cells is positively regulated by LNCAROD. This evidence concerns the gene FN1 and hepatocellular carcinoma.