To confirm the ability of KLF2 to promote differentiation of AML cells, we induced its expression in Fujioka cells (Figure 5G) and noted both upregulation of CD86 (Figure 5H) and reduction of clonogenic activity, with both fewer and smaller colonies in the presence of increased KLF2 expression (Figure 5I). This evidence concerns the gene CD86 and acute myeloid leukemia.