FOXC1 and acute myeloid leukemia: To further highlight the differentiation program induced by FOXC1 KD in Fujioka cells, we used gene set enrichment analysis (GSEA) to compare the transcriptional changes with, as an example, those observed during phorbol ester-mediated terminal differentiation of THP1 AML cells into macrophages (Suzuki et al., 2009; Figure S5A; Table S3).