The remaining genes were annotated as transposases (classified as integrative conjugative elements [ICEs] in Fig. 4B) or were virulence associated (n = 4), including three genes (yraJ, yraI, and yehB; homologs of genes in the Lpf and Stc fimbrial gene clusters in Salmonella) associated with chaperone-usher fimbria assembly and sopD2 encoding a secreted effector that blocks lysosome fusion with the Salmonella-containing vacuole during intracellular infection of host cells (23). The gene discussed is STC1; the disease is infection.