HMGCR and cancer: The top five genes were HMGCR, LDL1 (low‐density lipoprotein 1), ACAT2 (acetyl‐CoA acetyltransferase 2), NSDHL (NAD[P] dependent steroid dehydrogenase‐like), and LDLR1 (low‐density lipoprotein receptor 1) (Figure 5B), all of which were positively correlated with HMGCS1 in most cancer types (Figure 5C).