The top five genes were HMGCR, LDL1 (low‐density lipoprotein 1), ACAT2 (acetyl‐CoA acetyltransferase 2), NSDHL (NAD[P] dependent steroid dehydrogenase‐like), and LDLR1 (low‐density lipoprotein receptor 1) (Figure 5B), all of which were positively correlated with HMGCS1 in most cancer types (Figure 5C). This evidence concerns the gene HMGCS1 and cancer.