In Kaplan–Meier Plotter dataset, we found that higher level of HMGCS1 was linked to shorter OS in multiple tumor types, including BCA (bladder carcinoma), CSCA, HNSC, PDAC, SARC, UCEC, BRCA, CESC, CHOL, KICH, LUAD, MESO, and THCA (Figure 2A, C). This evidence concerns the gene BLNK and urinary bladder carcinoma.