Likewise, in an RF model that specifically focused on the subset of patients with CM with brain swelling, all 4 Group A–EPCR var transcripts (DBLα1.7-DC13, CIDRα1.5, CIDRα1.6, and CIDRα1.7) and a primer recognizing Group A dual EPCR and ICAM-1–binding parasites strongly discriminated brain swelling patients with mild thrombocytopenia from patients with UM (AUC, 0.91 [95% CI, 0.88–0.98]). The gene discussed is ICAM1; the disease is Thrombocytopenia.