Whereas individual var transcript levels did not differ between UM and CM cases by var domain typing (Figure 3A), both methodologies reported approximately 3 times higher proportions of Group A–EPCR and DC8-EPCR transcripts in patients with CM compared with the genome representation (~30% of var transcripts in patients with CM versus ~12.5% of PfEMP1 repertoire) (Figure 3, B and C) (28). This evidence concerns the gene PROCR and cutaneous mastocytosis.