Since several studies have reported on the role of TILs in the prognosis of ovarian cancer (21–24), and SLFN11 has been shown to be expressed in primary human T lymphocytes (16), we evaluated TIL infiltration by CD3 and CD8 staining, both in terms of total number (total CD3+ and CD8+ TILs) and of a measure of TILs in direct contact with cancer cells, without stroma interposition (intratumor CD3+ and CD8+ TILs) in HGSOC (19). This evidence concerns the gene CD8A and cancer.