LCAT and viral load: Exogenous: Lead intoxication, Metals and metalloids, Intoxication with Aristolochiaclematitis, Ochratoxin A and Pliocene lignite Endogenous: Genetic predisposition, LCAT enzyme deficiency, Genetic polymorphism, Chromosomal aberrations, Viral disease and Immunological factors Miscellaneous: Lecithin cholesterol acyltransferase and organic substances from coal