Several works have shown a correlation between high expression levels of Eg5 and poor prognosis in breast cancer [18], hepatocellular carcinoma [19], thymic malignancies [52], laryngeral squamous cell carcinoma [20], renal cell carcinoma [22] and in non-muscle invasive bladder urothelial carcionoma [39]. The gene discussed is KIF11; the disease is renal cell carcinoma.