Kinetics of cellular aging markers changed significantly between the day prior to infection (C-1) and day post treatment 1 (DT+1), with a significant decrease in TL (p = 0.004, Fig. 2D) and elevated CDKN2A expression levels upon DT+1 (p < 0.001, Fig. 2D); both markers were significantly correlated with parasite density (all p < 0.05, Fig. 2C). The gene discussed is CDKN2A; the disease is infection.