We also analyzed SON expression using publicly available patient databases (REMBRANDT; Repository of Molecular Brain Neoplasia Data31, R2 Database; http://r2.amc.nl, Oncomine32, Exon Expression Array33, GlioVis Data Portal; http://gliovis.bioinfo.cnio.es34) and corroborated our finding of SON upregulation in brain tumors (Fig. 1c and Supplementary Fig. 1a–c). The gene discussed is SON; the disease is brain neoplasm.