We further verified the above speculation by using cell experiments and found that relative to normal gastric epithelial cells (GES-1), KLF5 and DANCR were highly expressed in GC cell lines, while the expression of KLF5 and DANCR was the highest in the MGC-803 cell line, which was selected for subsequent experiments (Fig. 1G). This evidence concerns the gene KLF5 and gastric cancer.