Intriguingly, we observed a positive correlation between type 1 inflammatory mediators (e.g., IFNɣ and CXCL10) and eosinophil activation, suggesting that, particularly in moderately affected patients, part of the granulocyte compartment could be actively participating in the efficient viral clearance, similarly to what can occur upon influenza infection (50, 51). Here, IFNA1 is linked to influenza.