The amount of CD98 (MFI) expressed on CD8+ T cells was decreased in early HIV-infected cART–naïve individuals (565.2 ± 17.7 versus 599.7 ± 30.2) and this was more marked in chronic HIV-infected cART–treated infection (533.2 ± 9.9 versus 599.7 ± 30.2, *P = 0.0447) (Fig 5C). Here, CD8A is linked to infection.