ESR1 and neoplasm: Table 1 showed the clinical characteristics of these patients [including age, pathologic tumor size (pT), regional lymph node invasion (pN), AJCC stage, pathologic grade, whether the patients underwent adjuvant chemotherapy (AdjCTX) or adjuvant radiotherapy (AdjRAD)], and the patient numbers in each factor were all balanced in ER (+) and ER (−) groups according to Chi-squared tests.