IGHE and Alzheimer disease: Our earlier findings of the total immunoglobulin E (IgE‐), and the serum thymus and activation‐regulated chemokine (TARC) levels, and the history of shield ulcers in 5 patients with severe AD (serum TARC >1000 pg/ml) and 6 patients with severe AKC with giant papillae are shown in Table 1.