Similarly, a comparative analysis was conducted between open GEO database (GSE118916, GSE79973, GSE26942, GSE56807, and GSE54129) [45–48] in GC samples and non-carcinoma adjacent samples, revealing that ACTN1 was overexpressed in GC (P < 0.05) (Figure 1d). Here, ACTN1 is linked to carcinoma.