CTRL and type 2 diabetes mellitus: Representative dot-blot and protein quantification of ubiquitin-conjugated proteins (E), and chymotrypsin-like peptidase activity of the 26 S proteasome (+ ATP) (F) in OM preadipocytes from NG, IR, and T2D morbidly obese individuals exposed 14 hr to 0.5 mg/mL TUDCA, 24 hr to HGHI conditions, and/or a combination of both.