Therefore, the present study was designed to investigate the diagnostic value of hsa_circ_0001785 (Circ‐ELP3) and hsa_circ_100219 (Circ‐FAF1) in serum samples of breast cancer patients before and after an intervention to find out whether these circRNAs can utilize as a diagnostic and prognostic biomarker for human breast cancer assessment. The gene discussed is FAF1; the disease is breast cancer.