EZH2 and hepatocellular carcinoma: RT-qPCR and Western blot analysis were used to detect the expression of FOXP4-AS1, EZH2, H3K27me3, and ZC3H12D in HCC tissues and adjacent tissues; it was demonstrated that FOXP4-AS1 and EZH2 expression and H3K27me3 abundance were heightened and ZC3H12D expression was decreased in the HCC tissues versus the adjacent tissues (all P < 0.05) (Fig. 1A–G).