As a result, 36 crossover genes of 58 components in XXD were associated with AKI and are shown in Figure 3(a) such as TLR4, ACE, HSPA8, SIRT1, EGFR, HSPA1A, HMOX1, NOS2, NOS1, NOS3, ADRB2, PTGS2, MET, IL-6, CYP2E1, LGALS3, EPHX2, TTR, TNF, SLC22A12, MPO, MTOR, VEGFA, TP53, BCL2, CAPN1, PPARG, KLK1, MB, ALB, CASP1, ICAM-1, NFE2L2, NFKB1, HIF1A, and G6PD. Here, SIRT1 is linked to acute kidney injury.