As a result, 36 crossover genes of 58 components in XXD were associated with AKI and are shown in Figure 3(a) such as TLR4, ACE, HSPA8, SIRT1, EGFR, HSPA1A, HMOX1, NOS2, NOS1, NOS3, ADRB2, PTGS2, MET, IL-6, CYP2E1, LGALS3, EPHX2, TTR, TNF, SLC22A12, MPO, MTOR, VEGFA, TP53, BCL2, CAPN1, PPARG, KLK1, MB, ALB, CASP1, ICAM-1, NFE2L2, NFKB1, HIF1A, and G6PD. This evidence concerns the gene HMOX1 and acute kidney injury.