As a result, the targets of XXD were enriched in response to oxidative stress (GO:0006979), reactive oxygen species metabolic process (GO: 0072593), and cellular response to external stimulus (GO: 0071496), etc. Meanwhile, we observed that the HIF1 signaling pathway (hsa04066), proteoglycans in cancer (hsa05205), and Kaposi sarcoma-associated herpesvirus infection (hsa05167) were mainly involved with the 36 targets of 58 components in XXD. This evidence concerns the gene HIF1A and cancer.