To identify the putative transcription factors that regulate the expression of BUB1B/BUBR1, we investigated genes positively correlated with BUB1B/BUBR1 expression level (Spearman’s correlation coefficient >0.6) in TCGA datasets among various cancer types, followed by the extraction of putative human transcription factors [33] from these positively correlated genes (Fig. 6a). Here, BUB1B is linked to cancer.