Meantime, we also found that propranolol treatment could slightly enhance IFNα secretion compared with untreated group, and propranolol pretreatment could further enhance IFNα secretion compared with single treatment group after 9 h or 20 h virus infection (9 h: compared with propranolol group: #P < 0.05; compared with T1012G group: &&P < 0.01; 20 h: compared with propranolol group: ##P < 0.01; compared with T1012G group: &&P < 0.01;Fig. 7C), while there was no significant effect on the secretion of IFNβ (P > 0.05; Fig. 7D). Here, IFNB1 is linked to viral infectious disease.